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Clinical impact of assay of estrogen receptor βcx in breast cancer

✍ Scribed by Shigehira Saji; Yoko Omoto; Chikako Shinizu; Shin-ichiro Horiguchi; Toru Watanabe; Nobuaki Funata; Shin-ichi Hayashi; Jan-Åke Gustafsson; Masakazu Toi

Publisher
Springer Japan
Year
2002
Tongue
English
Weight
712 KB
Volume
9
Category
Article
ISSN
1340-6868

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Estrogen receptor (ER) content is the most useful parameter for predicting hormone response therapy in breast cancer. Assays available for detecting ER in breast tumor cytosol are ligand-binding assay (LBA), which detects both ER␣ and ER␤, and the enzymatic immunoassay (EIA), in which monoclonal ant