✦ LIBER ✦

Clinical guidelines for the management of pouchitis

✍ Scribed by Darrell S. Pardi; Geert D'Haens; Bo Shen; Simon Campbell; Paolo Gionchetti

Publisher: John Wiley and Sons
Year: 2009
Tongue: English
Weight: 207 KB
Volume: 15
Category: Article
ISSN: 1078-0998
DOI: 10.1002/ibd.21039

No coin nor oath required. For personal study only.

✦ Synopsis

When surgery is necessary in patients with ulcerative colitis, total proctocolectomy with ileal pouch-anal anastomosis (IPAA) is the procedure of choice. Several inflammatory and noninflammatory complications can occur after IPAA. Pouchitis is the most common, occurring in approximately 50% of patients. Whereas "acute" pouchitis can be treated rapidly and successfully in the majority of patients, "refractory" and "chronic pouchitis" remain therapeutic challenges to patients and physicians. This article reviews the literature and offers consensus guidelines on issues related to the epidemiology, diagnosis, pathogenesis, risk factors, and treatment of pouchitis.

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