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Clinical grade preparation of human natural regulatory T-cells encoding the thymidine kinase suicide gene as a safety gene: authors' reponse

✍ Scribed by Maude Guillot-Delost; Mustapha Cheraï; Yamina Hamel; Michelle Rosenzwajg; Claude Baillou; Ghislaine Simonin; Virginie Leclercq; Maria Encarnita Mariotti-Ferrandiz; Adrien Six; Véronique Bon-Durand; Sébastien Maury; Benoit L. Salomon; José L. Cohen; David Klatzmann; François M. Lemoine

Publisher: John Wiley and Sons
Year: 2009
Tongue: English
Weight: 46 KB
Volume: 11
Category: Article
ISSN: 1099-498X
DOI: 10.1002/jgm.1358

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✦ Synopsis

Abstract

This Response refers to JGM 1286, which was published in The Journal of Gene Medicine 11:2. Please follow the link below to view the Letter to the Editor.

Letter to the Editor

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Clinical-grade preparation of human natu

Clinical-grade preparation of human natural regulatory T-cells encoding the thymidine kinase suicide gene as a safety gene

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## Abstract ## Background Human CD4^+^CD25^+^FOXP3^+^ natural regulatory T‐cells (nTreg) have a great therapeutic potential for the induction of tolerance in allo‐transplanted patients or for the control of severe auto‐immune diseases. However, clinical‐grade production of nTreg remains difficult

Comment on M. Guillot-Delost et al. (200

Comment on M. Guillot-Delost et al. (2008;10:834-846): Clinical-grade preparation of human natural regulatory T cells encoding the thymidine kinase suicide gene as a safety gene

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