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Clinical experience with R103757, a potent inhibitor of microsomal triglyceride transfer protein (MTP)

โœ Scribed by A.G. Dupont; J. De Cree; R. Vermeulen; W. Salvo; F. Deridder

Book ID
119438943
Publisher
Elsevier Science
Year
1999
Tongue
English
Weight
147 KB
Volume
144
Category
Article
ISSN
0021-9150

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Microsomal triglyceride transfer protein
Microsomal triglyceride transfer protein (MTP) gene mutations in Canadian subjects with abetalipoproteinemia
โœ Jian Wang; Robert A. Hegele ๐Ÿ“‚ Article ๐Ÿ“… 2000 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 19 KB

Abetalipoproteinemia (ABL) is an extremely rare autosomal recessive disorder, which is characterized by defective assembly and secretion of plasma apolipoprotein (apo) Bcontaining lipoproteins. ABL results from mutations in the gene encoding the microsomal triglyceride transfer protein (MTP). We seq