𝔖 Bobbio Scriptorium
✦   LIBER   ✦

CLINICAL EXPERIENCE WITH NUCLEOSIDES IN HERPES SIMPLEX EYE INFECTIONS IN MAN AND ANIMALS

✍ Scribed by Irving H. Leopold

Book ID
114877485
Publisher
John Wiley and Sons
Year
2006
Tongue
English
Weight
583 KB
Volume
130
Category
Article
ISSN
0890-6564

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## Abstract Herpes simplex virus (HSV) resistance to acyclovir or foscarnet results from mutations in viral thymidine kinase (TK) and/or DNA polymerase (pol) genes. Replication kinetics and virulence of TK and/or DNA pol clinical mutants were assessed using models of mouse encephalitis and cotton r