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Clinical experience with Hemofil M in a hemophilia patient exhibiting inhibitors

โœ Scribed by J. Ingerslev; K. Wallevik

Book ID
105282467
Publisher
Springer
Year
1991
Tongue
English
Weight
208 KB
Volume
63
Category
Article
ISSN
0939-5555

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Six frameshift mutations in exon 14 of the factor VIII gene were identified in Thai hemophilia A patients. Although all these mutations created premature stop codons and expected to cause severe disease, the molecular defects and clinical severity were in discrepancy in some patients. Four mutations