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Clinical experience of tolcapone in advanced Parkinson’s disease

✍ Scribed by Margherita Canesi; Anna Lena Zecchinelli; Gianni Pezzoli; Angelo Antonini

Book ID
106268624
Publisher
Springer Milan
Year
2008
Tongue
English
Weight
39 KB
Volume
29
Category
Article
ISSN
1590-1874

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## Abstract This double‐blind study examined the efficacy and safety of replacing entacapone with tolcapone in fluctuating Parkinson's disease (PD) patients. Patients receiving entacapone for ≥15 days were randomly assigned to continue entacapone (n = 75) or switch to tolcapone (n = 75) and were fo