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Clinical experience of encainide (MJ 9067): A new anti-arrhythmic drug

โœ Scribed by H. Kesteloot; R. Stroobandt


Publisher
Springer
Year
1979
Tongue
English
Weight
488 KB
Volume
16
Category
Article
ISSN
0031-6970

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Species differences in the pharmacokinet
โœ J. A. Scatina; H. B. Kimmel; V. Weinstein; S. M. Troy; S. F. Sisenwine; M. N. Ca ๐Ÿ“‚ Article ๐Ÿ“… 1990 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 774 KB

## Abstract The pharmacokinetics of recainam, an antiโ€arrhythmic drug, were compared in mice, rats, rabbits, dogs, rhesus monkeys, and man, Bioavailability was virtually complete in monkeys and dogs, 67 per cent in man and 51 per cent in rats. Nonโ€linear kinetics between the oral and i.v. dose in r