Three novel monoclonal antibodies (MAbs) were established against a recombinant hepatitis C virus (HCV) core protein derived from cloned genotype 1 b HCV cDNA. MAbs C7-50 and C8-59 recognize a conserved linear epitope represented by amino acid residues 21 to 40 of the nucleocapsid protein. MAb C8-48
Clinical evaluation of the antibody against core protein of hepatitis C virus
β Scribed by Ohkoshi, Showgo ;Watanabe, Masashi ;Kuwana, Kenji ;Tawaraya, Hironobu ;Kamimura, Tomoteru ;Asakura, Hitoshi
- Publisher
- Springer-Verlag
- Year
- 1993
- Tongue
- English
- Weight
- 286 KB
- Volume
- 28
- Category
- Article
- ISSN
- 0435-1339
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
We have cloned the whole structural region of the hepatitis C virus (HCV) genome and transiently expressed the nucleocapsid protein in animal cells. Since the nucleotide sequences of this region of the HCV genome has been shown to be highly conserved among different HCV isolates, the assay detecting
## Abstract The binding sites for human antibodies recognising antigenic domains within the hepatitis C virus (HCV) core protein were analyzed using synthetic peptides. Omission peptide analogues where a pair of residues was sequentially omitted were produced corresponding to the regions 1β18, 11β2