Clinical Efficacy and Safety of Successful Longterm Urate Lowering with Febuxostat or Allopurinol in Subjects with Gout
β Scribed by BECKER, M. A.; SCHUMACHER, H. R.; MacDONALD, P. A.; LLOYD, E.; LADEMACHER, C.
- Book ID
- 111982025
- Publisher
- Journal of Rheumatology Publishing Company
- Year
- 2009
- Tongue
- English
- Weight
- 535 KB
- Volume
- 36
- Category
- Article
- ISSN
- 0315-162X
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π SIMILAR VOLUMES
## Abstract ## Objective To compare the urateβlowering efficacy and safety of febuxostat, allopurinol, and placebo in a large group of subjects with hyperuricemia and gout, including persons with impaired renal function. ## Methods Subjects (n = 1,072) with hyperuricemia (serum urate level β₯8.0
## Abstract ## Objective Gout affects βΌ1β2% of the American population. Current options for treating hyperuricemia in chronic gout are limited. The purpose of this study was to assess the safety and efficacy of febuxostat, a nonpurine selective inhibitor of xanthine oxidase, in establishing normal