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Clinical Efficacy and Safety of Successful Longterm Urate Lowering with Febuxostat or Allopurinol in Subjects with Gout

✍ Scribed by BECKER, M. A.; SCHUMACHER, H. R.; MacDONALD, P. A.; LLOYD, E.; LADEMACHER, C.


Book ID
111982025
Publisher
Journal of Rheumatology Publishing Company
Year
2009
Tongue
English
Weight
535 KB
Volume
36
Category
Article
ISSN
0315-162X

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πŸ“œ SIMILAR VOLUMES


Effects of febuxostat versus allopurinol
✍ Schumacher, H. RALPH ;Becker, Michael A. ;Wortmann, Robert L. ;MacDonald, Patric πŸ“‚ Article πŸ“… 2008 πŸ› John Wiley and Sons 🌐 English βš– 152 KB πŸ‘ 1 views

## Abstract ## Objective To compare the urate‐lowering efficacy and safety of febuxostat, allopurinol, and placebo in a large group of subjects with hyperuricemia and gout, including persons with impaired renal function. ## Methods Subjects (n = 1,072) with hyperuricemia (serum urate level β‰₯8.0

Febuxostat, a novel nonpurine selective
✍ Michael A. Becker; H. Ralph Schumacher Jr.; Robert L. Wortmann; Patricia A. MacD πŸ“‚ Article πŸ“… 2005 πŸ› John Wiley and Sons 🌐 English βš– 168 KB πŸ‘ 3 views

## Abstract ## Objective Gout affects ∼1–2% of the American population. Current options for treating hyperuricemia in chronic gout are limited. The purpose of this study was to assess the safety and efficacy of febuxostat, a nonpurine selective inhibitor of xanthine oxidase, in establishing normal