Clinical effects of combination therapy with mitoxantrone, vincristine, and prednisolone in breast cancer
β Scribed by Kenji Katsumata; Hidenori Tomioka; Mikihiro Kusama; Tatsuya Aoki; Yasuhisa Koyanagi
- Publisher
- Springer
- Year
- 2003
- Tongue
- English
- Weight
- 149 KB
- Volume
- 52
- Category
- Article
- ISSN
- 0344-5704
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
In our wide experience of treating advanced breast carcinoma with chemotherapy, the combination of doxorubicin (DOX), vincristine (VCR), cyclophosphamide (CPM) and fluorouracil (FU) gave a complete plus partial response rate of over 60%, with 100% alopecia and frequent cardiac toxicity depending on
In this study, 30 evaluable patients with advanced carcinoma of the breast were treated with cyclophosphamide 600 mg/m2 i.v. followed one day later with mitoxantrone (Novantrone; dihydroxyanthracenedione) 16 mg/m2 i.v. Drug treatment was repeated every 3-4 weeks, for a maximum of 12 cycles. The over
## Abstract We assessed whether split dosing with the methylating agent DTIC is an effective strategy for inactivating the DNA repair protein __O__6βalkylguanine DNAβATase in order to decrease tumour resistance to BCNU. ATase levels in PBMCs were used as a surrogate for tumour ATase depletion to de