Limited evidence suggests increased efficacy of rhG-CSF by subcutaneous (SQ) compared with intravenous (IV) administration. To examine the possibility that rapid elimination of IV rhG-CSF could substantially shorten the duration of systemic exposure and could explain a difference in pharmacodynamics
โฆ LIBER โฆ
Clinical effects and pharmacokinetics of the fusion protein PIXY321 in children receiving myelosuppressive chemotherapy
โ Scribed by Wayne L. Furman; John H. Rodman; Margaret E. Tonda; Xiaolong Luo; Bettye Arnold; Neyssa Marina; Leslie Garrison; Roberta Hanna; Charles B. Pratt; William H. Meyer
- Publisher
- Springer
- Year
- 1997
- Tongue
- English
- Weight
- 219 KB
- Volume
- 41
- Category
- Article
- ISSN
- 0344-5704
No coin nor oath required. For personal study only.
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## Abstract ## Background and Objectives p53 tumor suppressor gene has a dual role as a trigger of apoptosis and as an initiator of DNA repair. The Bclโ2 can work to protect cells from apoptosis, which is induced by p53 gene. These facts suggest the significant role of these genes in the genesis a