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Clinical diagnosis and therapy of cutaneous melanoma in situ

✍ Scribed by Cesare Bartoli; Aldo Bono; Claudio Clemente; Ivan Del Prato; Stefano Zurrida; Natale Cascinelli

Publisher
John Wiley and Sons
Year
1996
Tongue
English
Weight
428 KB
Volume
77
Category
Article
ISSN
0008-543X

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✦ Synopsis

BACKGROUND.

The frequency of in situ melanoma is increasing, and it is often diagnosed fortuitously by histology.

METHODS.

We retrospectively reviewed 121 melanomas in situ in 113 patients with the aim of identifylng the clinical features of, and optimal surgical treatment for this cutaneous malignancy. Treatment was limited surgery with 3 mm margins of excision in 69 cases (57%) and wider margins of excision (more than 3 mm) in 52 cases (43%). The lesions had a median diameter of 1 cm (range, 2-35 mm) and were generally macular (92% of cases) and asymmetric (87%), with an irregular border (88%) and nonuniform pigmentation (98%), usually in shades of brown (41%) and black (48%). These features had permitted a clinical diagnosis of melanoma or suspected melanoma in 62% of cases and of doubtful nevus in an additional 18% of cases.

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The authors thank the staff of the Cancer Registry of Western Australia, the private and public pathology laboratories, the hospitals and clinicians in Western Australia for their assistance in supplying information.