**Background**: Various agents have been implicated in causing tissue necrosis after intravenous infusions have extravasated. These include solutions of calcium, potassium, bicarbonate, hypertonic dextrose, cytotoxic drugs and antibiotics. Views on management of these injuries differ, and range from
Clinical course and management of accidental adriamycin extravasation
โ Scribed by James J. Reilly; James P. Neifeld; Steven A. Rosenberg
- Publisher
- John Wiley and Sons
- Year
- 1977
- Tongue
- English
- Weight
- 539 KB
- Volume
- 40
- Category
- Article
- ISSN
- 0008-543X
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๐ SIMILAR VOLUMES
In a material consisting of approximately 6,000 injections of Adriamycin during a 2-year period, eleven moderate and five severe extravasation injuries have been observed. Even a small leakage of the drug may cause a permanent lesion. The most serious injuries were caused by large doses and on the d
## Abstract ## Background To analyze the clinical course of pancreatoblastoma in children and to propose management and therapy. ## Procedure Retrospective review of seven cases of pancreatoblastoma treated in France over a 20โyear period and literature review. ## Results Median age of patient
Extravasation of doxorubicin and its derivative epirubicin, cause severe progressive tissue necrosis that requires early excision of all affected tissues. Doxorubicin and epirubicin are autofluorescent and this characteristic can be used to demonstrate and delineate extravasation by the aid of fluor