✦ LIBER ✦

Clinical characteristics of malignant melanomas developing in persons with dysplastic nevi

✍ Scribed by Jason K. Rivers; Alfred W. Kopf; Anne F. Vinokur; Darrell S. Rigel; Robert J. Friedman; Marcia Levenstein; Edward R. Heilman

Publisher: John Wiley and Sons
Year: 1990
Tongue: English
Weight: 471 KB
Volume: 65
Category: Article
ISSN: 0008-543X
DOI: 10.1002/1097-0142(19900301)65:5<1232::aid-cncr2820650533>3.0.co;2-8

No coin nor oath required. For personal study only.

✦ Synopsis

A total of 452 patients with dysplastic nevi (DN) were followed prospectively by repetitive, complete cutaneous examinations in order to determine the clinical features of early malignant melanomas (MM) arising in them. Sixteen patients (3.5%) developed 18 newly diagnosed MM during an average follow-up period of 27 months. Twelve of the 18 M M were in situ and all of the primary invasive M M diagnosed prospectively in this follow-up were less than 0.89 mm in Breslow thickness, implying an excellent prognosis. The principal clinical clue to the diagnosis of M M was change in a preexisting pigmented lesion. Totalbody photographs were very useful in helping to identify the early M M in these patients.

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