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Clinical characteristics and prognostic markers in disulfiram-induced liver injury

✍ Scribed by Einar Björnsson; Hans Nordlinder; Rolf Olsson

Book ID
116651023
Publisher
Elsevier Science
Year
2006
Tongue
English
Weight
238 KB
Volume
44
Category
Article
ISSN
0168-8278

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The combination of high aminotransferases (hepatocellular injury) and jaundice has been reported to lead to a mortality rate of 10% to 50% for different drugs, a phenomenon known as "Hy's rule." However, Hy's rule has never been validated, and limited data exist on predictors for outcome in hepatoce