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Clinical changes and EEG patterns preceding the onset of periodic sharp complexes in Creutzfeldt — Jakob disease

✍ Scribed by H.-C. Hansen; S. Zschocke; H.-J. Stürenburg; K. Kunze


Book ID
109336747
Publisher
John Wiley and Sons
Year
2009
Tongue
English
Weight
659 KB
Volume
97
Category
Article
ISSN
0001-6314

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## Abstract Experimental evidence and computer modeling indicate that periodic synchronous cellular depolarizing bursts (interictal spikes) arise when the balance between recurrent inhibition and local excitatory coupling is altered. Such a mechanism may explain the generalized periodic sharp waves