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Clinical Assessment and Efficacy of Once-Yearly Intravenous Zoledronic Acid in Korean Osteoporosis Patients

✍ Scribed by Park, Y.-S.; Lee, J.-H.; Kim, H.-S.


Book ID
125827967
Publisher
Elsevier Science
Year
2014
Tongue
English
Weight
42 KB
Volume
17
Category
Article
ISSN
1094-6950

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Zoledronic acid (ZOL), a third-generation aminobisphosphonate, showed pronounced antifracture efficacy in a phase III clinical trial [Health Outcomes and Reduced Incidence with Zoledronic Acid Once Yearly-Pivotal Fracture Trial (HORIZON-PFT)] when administered yearly (5-mg infusions of ZOL), produci

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## Abstract Zoledronic acid (ZOL) has shown beneficial effects on bone turnover and bone mineral density (BMD) in postmenopausal osteoporosis. This study compared the efficacy and safety of a once‐yearly i.v. infusion of ZOL with weekly oral alendronate (ALN) in men with osteoporosis. In this multi