## Abstract Specific estrogen, progesterone and androgen receptors were determined in 19 wellโcharacterized squamousโcell carcinoma (SCC) cell lines. Ten of the lines were derived from patients with SCC of the larynx and nine were from patients with SCC originating in other areas of the head and ne
Clinical aspects of steroid hormone receptors in human renal cell carcinoma
โ Scribed by James P. Karr; J. Edson Pontes; Sara Schneider; Avery A. Sandberg; Gerald P. Murphy
- Publisher
- John Wiley and Sons
- Year
- 1983
- Tongue
- English
- Weight
- 751 KB
- Volume
- 23
- Category
- Article
- ISSN
- 0022-4790
No coin nor oath required. For personal study only.
โฆ Synopsis
A review of the role of steroid hormone receptors and hormonal dependence of renal cell carcinoma in certain patients is presented. The results of a cumulative series of estrogen, progesterone, and androgen receptor assays performed on 48 normal and malignant human renal tumor specimens are given. The detectable presence of receptor proteins in certain patients could obviate the empirical use of hormonal therapy, an issue that may be resolved through a randomized multiinstitutional trial.
๐ SIMILAR VOLUMES
Female gender is a significant independent favorable prognostic factor in lung cancer. To study the possible role of sex hormones in lung cancer, the expression of sex-steroid receptors and the glucocorticoid receptor was investigated in 29 lung-cancer cell lines stemming from small-cell lung cancer
## Abstract Progesterone receptor was measured in eight samples of renal cell carcinoma, nine samples of normal renal tissue, and one sample of melanoma tissue. Progesterone receptor was identified in all samples, with the exception of one renal cell carcinoma. Three patients, all with receptorโpos
## Abstract Since a number of renalโcell carcinomas regress with hormonal manipulation, we have identified and measured the levels of estrogen, progestin and glucocorticoid receptors in 47 autologous pairs of normal and neoplastic kidney tissues. Highโaffinity receptors for these hormones were dete