Long-term effects of LDL apheresis in pa
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Bruce S. Sachais; Julie Katz; Joyce Ross; Daniel J. Rader
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Article
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2005
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John Wiley and Sons
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English
β 117 KB
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Familial hypercholesterolemia (FH) is an inherited disorder of lipoprotein metabolism involving mutations in the LDL receptor (LDL-R). Patients with mutation in one (heterozygous) or both (homozygous) genes have markedly elevated LDL cholesterol and are at increased risk for coronary heart disease (