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Clinical applications of long-term LDL-apheresis on and beyond refractory hypercholesterolemia

✍ Scribed by Hiroshi Mabuchi; Toshinori Higashikata; Masa-aki Kawashiri


Book ID
116928314
Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
366 KB
Volume
30
Category
Article
ISSN
1473-0502

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Familial hypercholesterolemia (FH) is an inherited disorder of lipoprotein metabolism involving mutations in the LDL receptor (LDL-R). Patients with mutation in one (heterozygous) or both (homozygous) genes have markedly elevated LDL cholesterol and are at increased risk for coronary heart disease (