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Clinical applications of diffusion tensor imaging

✍ Scribed by Qian Dong; Robert C. Welsh; Thomas L. Chenevert; Ruth C. Carlos; Pia Maly-Sundgren; Diana M. Gomez-Hassan; Suresh K. Mukherji

Publisher
John Wiley and Sons
Year
2003
Tongue
English
Weight
790 KB
Volume
19
Category
Article
ISSN
1053-1807

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✦ Synopsis

Abstract

Directionally‐ordered cellular structures that impede water motion, such as cell membranes and myelin, result in water mobility that is also directionally‐dependent. Diffusion tensor imaging characterizes this directional nature of water motion and thereby provides structural information that cannot be obtained by standard anatomic imaging. Quantitative apparent diffusion coefficients and fractional anisotropy have emerged from being primarily research tools to methods enabling valuable clinical applications. This review describes the clinical utility of diffusion tensor imaging, including the basic principles of the technique, acquisition, data analysis, and the major clinical applications. J. Magn. Reson. Imaging 2004;19:6–18. © 2003 Wiley‐Liss, Inc.

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