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Clinical application of molecular markers in stage I non-small cell lung cancer: Prognostic value of p53 and p16 abnormalities

✍ Scribed by Niklinski, J; Chyczewski, L; Niklinska, W.E; Laudanski, J; Chyczewska, E; Lapuc, G


Book ID
118570273
Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
118 KB
Volume
29
Category
Article
ISSN
0169-5002

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Accumulation of mutant p53 protein occurs frequently in human malignancies, including 40-60% of non-small cell lung carcinomas. The implications of such p53 over-expression, usually assessed by immunohistochemical techniques, for the prognosis of lung cancer patients remain undetermined. In this stu