Absolute proof of efficacy can only be given by placebo controlled trials. It is, however, important to classify a drug within the spectrum of existing therapeutic alternatives and, where effective treatment is available, it may be imperative due to ethical considerations to demonstrate that one dru
β¦ LIBER β¦
Clinical and statistical issues related to predicting therapeutic outcome
β Scribed by William B. Ghiselli
- Publisher
- John Wiley and Sons
- Year
- 1983
- Tongue
- English
- Weight
- 471 KB
- Volume
- 39
- Category
- Article
- ISSN
- 0021-9762
No coin nor oath required. For personal study only.
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## Abstract It has been suggested that preoperative measurement of resting anal canal pressure and internal sphincter function can be used to identify those patients with neurogenic faecal incontinence who are unlikely to benefit from the operation of postanal repair. We have therefore analysed the