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Clinical and physiological findings in the skin of patients with the common melas mutation in mitochondrial DNA

โœ Scribed by Karvonen, S-L.; Haapasaari, K-M.; Kallioinen, M.; Oikarinen, A.; Hassinen, I.E.; Majamaa, K.


Book ID
119562377
Publisher
Elsevier Science
Year
1998
Tongue
English
Weight
175 KB
Volume
16
Category
Article
ISSN
0923-1811

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Clinical, physiological, and histologica
โœ M.A. Tarnopolsky; J. Maguire; T. Myint; D. Applegarth; B.H. Robinson ๐Ÿ“‚ Article ๐Ÿ“… 1998 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 912 KB

The majority of patients with MELAS syndrome (mitochondrial myopathy, encephalopathy, lactic acidosis, and strokelike episodes) have an Aโ†’G mutation at nucleotide 3243 in mitochondrial transfer (t)RNA. To date there have only been 10 reported cases of MELAS syndrome in patients with a Tโ†’C mutation a