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Clinical and laboratory features of scleroderma patients developing skeletal myopathy

✍ Scribed by Yoshihiro Mimura; Hironobu Ihn; Masatoshi Jinnin; Yoshihide Asano; Kenichi Yamane; Kunihiko Tamaki


Publisher
Springer
Year
2004
Tongue
English
Weight
178 KB
Volume
24
Category
Article
ISSN
0770-3198

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Mitochondrial myopathies: Clinical and b
✍ I. J. Holt; Dr A. E. Harding; J. M. Cooper; A. H. V. Schapira; A. Toscano; J. B. πŸ“‚ Article πŸ“… 1989 πŸ› John Wiley and Sons 🌐 English βš– 908 KB

Analysis of mitochondrial DNA (mtDNA) in muscle and blood from 72 patients with mitochondrial myopathy showed that 30 had major deletions of a variable proportion of muscle mtDNA. All of these 30 patients presented with progressive external ophthalmoplegia and limb weakness, and 8 had the additional