𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Clinical and economic analysis of spa therapy in Parkinson's disease

✍ Scribed by Christine Brefel-Courbon; Karine Desboeuf; Claire Thalamas; Monique Galitzky; Jean-Michel Senard; Olivier Rascol; Jean-Louis Montastruc


Publisher
John Wiley and Sons
Year
2003
Tongue
English
Weight
455 KB
Volume
18
Category
Article
ISSN
0885-3185

No coin nor oath required. For personal study only.

✦ Synopsis


The effectiveness of spa therapy in the management of patients with Parkinson's disease (PD) has never been evaluated. This is assessed in this pilot study. A prospective, randomized, cross-over, controlled study was conducted in 31 PD patients who underwent a 20-week spa period, including spa therapy for 3 weeks, and a 20-week non-spa period. Effectiveness was assessed using quality of life scales (PDQ-39 and SF-36), motor scale (UPDRS) and psychological questionnaire (GHQ-28), at baseline and at 4 (T4) and at 20 weeks (T20). Direct medical costs (radiological and laboratory tests, physician fees, drug therapy, and ancillary care) were recorded over each 20-week period. At T4, spa therapy improved significantly several dimensions of PDQ-39 and SF-36, part IV of the UPDRS, and GHQ-28. At T20, no difference in any parameter was found. The mean direct medical cost over 20 weeks (euro;1,328 +/- 167; pound 776 +/- 97 per patient) in the spa period was slightly but significantly reduced in comparison with that of the non-spa period (euro;1380 +/- 523; pound 807 +/- 306 per patient). This cost-effectiveness analysis suggests that spa therapy is more effective and less expensive than conventional treatment alone and could be beneficial in the management of PD.


πŸ“œ SIMILAR VOLUMES


Clinical implications of gene discovery
✍ Christian Wider; Tatiana Foroud; Zbigniew K. Wszolek πŸ“‚ Article πŸ“… 2010 πŸ› John Wiley and Sons 🌐 English βš– 76 KB

## Abstract Over the past decade, major progress has been achieved in the identification of genes associated with Parkinson's disease (PD) and parkinsonism. Five genes have now been shown conclusively to play a role in PD susceptibility. Mutations in three of these genes, __PRKN__, __PINK1,__ and _

Clinical measures of progression in Park
✍ Werner Poewe πŸ“‚ Article πŸ“… 2009 πŸ› John Wiley and Sons 🌐 English βš– 76 KB πŸ‘ 1 views

## Abstract Despite all recent advances in symptomatic therapy Parkinson's disease (PD) continues to be a relentlessly progressive neurodegenerative disorder. Therefore therapies that will slow or hold disease progression are a major medical unmet need in PD. Clinical measures of disease progressio