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Clinical and cerebral activity changes induced by subthalamic nucleus stimulation in advanced Parkinson's disease: A prospective case-control study

✍ Scribed by Roberto Cilia; Giorgio Marotta; Andrea Landi; Ioannis U. Isaias; Claudio B. Mariani; Francesco Vergani; Riccardo Benti; Erik Sganzerla; Gianni Pezzoli; Angelo Antonini


Book ID
116369490
Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
632 KB
Volume
111
Category
Article
ISSN
0303-8467

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## Abstract Patients with advanced Parkinson's disease (PD) develop disabling axial symptoms, including gait disturbances, freezing and postural instability poorly responsive to levodopa replacement therapy. The pedunculopontine nucleus (PPN) is involved in locomotion, control of posture, and behav