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Clinical and biological significance of RAS mutations in multiple myeloma

✍ Scribed by Chng, W J; Gonzalez-Paz, N; Price-Troska, T; Jacobus, S; Rajkumar, S V; Oken, M M; Kyle, R A; Henderson, K J; Van Wier, S; Greipp, P

Book ID
109886495
Publisher
Nature Publishing Group
Year
2008
Tongue
English
Weight
131 KB
Volume
22
Category
Article
ISSN
0887-6924

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## Abstract __Ras__ gene mutations are a recurrent genetic lesion in multiple myeloma (MM). Here, we report a mutation analysis of N‐ and K‐__Ras__ genes in purified plasma cell populations from a panel of 81 newly diagnosed MM patients stratified according to the most frequent genetic and molecula