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Clinical and biologic effects of combination therapy with gamma-interferon and tumor necrosis factor

✍ Scribed by Joan H. Schiller; Patricia L. Witt; Barry Storer; Dona Alberti; Mary Beth Tombes; Rhoda Arzoomanian; Raymond R. Brown; Richard A. Proctor; Stephan D. Voss; David R. Spriggs; Donald L Trump; Ernest C. Borden

Publisher
John Wiley and Sons
Year
1992
Tongue
English
Weight
894 KB
Volume
69
Category
Article
ISSN
0008-543X

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## Background: Isolated limb perfusion (ilp) with tumor necrosis factor alpha (tnf alpha) +/-interferon gamma (ifn gamma) and melphalan in patients with primarily irresectable soft tissue sarcoma is promising in terms of tumor regression and limb salvage. however, the feasibility of radiotherapy in