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Clinical and biochemical effects of zileuton in patients with the Sjögren-Larsson syndrome

✍ Scribed by Michèl A. Willemsen,Monique A. Lutt,Peter M. Steijlen…


Book ID
113043090
Publisher
Springer
Year
2001
Tongue
English
Weight
118 KB
Volume
160
Category
Article
ISSN
0340-6997

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The gene encoding the human fatty aldehyde dehydrogenase (FALDH) is located on 17p11.2, causing Sjögren-Larsson syndrome (SLS) when mutated. SLS is an autosomal recessive disorder characterized by a combination of mental retardation, congenital ichthyosis, and spastic di-or tetraplegia. We report he