Clerodane and aromatic seco-clerodane diterpenoids from salvia rhyacophua.

✍ Scribed by María del Carmen Fernández; Baldomero Esquivel; Jorge Cárdenas; Ana Adela Sánchez; Ruben Alfredo Toscano; Lydia Rodríguez-Hahn

• Book ID: 104204899
• Publisher: Elsevier Science
• Year: 1991
• Tongue: French
• Weight: 600 KB
• Volume: 47
• Category: Article
• ISSN: 0040-4020
• DOI: 10.1016/s0040-4020(01)89722-2

✦ Synopsis

Abstrsct-The known cIcrodane Qterpenes salvisnn 1 and 6p-hydroxy-7,8-dehydrobscche~riconsctm 2, were dilated from Sulwa rhyzcophdu together wllh tivc new dcrodane cbterpenolds 34 and I2 The struch~res of ditcrpcncs 3-6 we= wtabllshed on spcchal cvldencc and chemxal tmnsformatlons Rhyacophdme IS an aromatic seco-clerodsne dlterpenold whose sbuc1um 12 wss cstsbhshed by spectral mcalg and X-ray dlffracbon analysis Angulatae (SubsectIon Tduzefolrae) Recently we descrtbed5 the unusual dlterpenold constituents Isolated from S trlraefolra, a species consrderedl representative of this SectIon Results and Discussion From the polar fraction of the aerial parts of S. rhyacophrla, salvlarm 1 was Isolated as the major (0 08 % dry wt) dlterpene component Salvlarm had been previously found m S. splendens, 6 a species endemic to Brazil, which has been classlfled' In Sectlon Secundae ( Salvta, Subgenus Calosphace) The known 6$-hydroxy-7,8_dehydrobacchatrlcunaetm 2, previously obtamed' from Aster alpmus (Composuae )was also Isolated from S rhyacophda together with five new clerodane dlterpenolds *Contnbutlon No 1057 from the Instltuto de Quimtca