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Cleft palate induction in strain a mice with cortisone

✍ Scribed by Isaacson, Robert J. ;Chaudhry, A. P.


Publisher
John Wiley and Sons
Year
1962
Tongue
English
Weight
443 KB
Volume
142
Category
Article
ISSN
0003-276X

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## Abstract ## BACKGROUND: Gamma‐aminobutyric acid is an inhibitory neurotransmitter, synthesized by two isoforms of glutamate decarboxylase (GAD), GAD65 and ‐67. Unexpectedly, inactivation of __GAD67__ induces cleft palate in mice. Reduction of spontaneous tongue movement resulting from decreased