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Cleavage of the retinal pigment epithelium-specific protein RPE65 under oxidative stress

✍ Scribed by Hyunju Lee; Hyewon Chung; Hilal Arnouk; Folami Lamoke; Richard C. Hunt; William J.M. Hrushesky; Patricia A. Wood; Sung Haeng Lee; Wan Jin Jahng


Book ID
116542319
Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
254 KB
Volume
47
Category
Article
ISSN
0141-8130

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The retinal pigment epithelium (RPE) is essential for retinoid recycling and phagocytosis of photoreceptors. Understanding of proteome changes that mediate oxidative stress-induced degeneration of RPE cells may provide further insight into the molecular mechanisms of retinal diseases. In the current