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Cleavage of the N(1)C(4) bond of 4-(4′-hydroxyphenyl)-azetidine-2-ones via quinone methide intermediates

✍ Scribed by Larry A Cabell; Loren W Hedrich; John S McMurray

Book ID: 104231896
Publisher: Elsevier Science
Year: 2001
Tongue: French
Weight: 80 KB
Volume: 42
Category: Article
ISSN: 0040-4039
DOI: 10.1016/s0040-4039(01)01849-4

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## Abstract magnified image The synthesis of a novel series of analogous intermediates __N__^3^‐[1‐alkyl(aryl/heteroaryl)‐3‐oxo‐4,4,4‐trichloroalk‐1‐en‐1‐yl]‐2,3‐diaminopyridines and __N__^2^‐(methanesulfonyl) [Cl~3~CC(O)CHCRNH(C~5~H~3~N)NHY], where R = H, Me, C~6~H~5~, 4‐FC~6~H~4~, 4‐ClC~6~H~4~