Cleavage of Rabbit Myelin Basic Protein by Pepsin
β Scribed by Russell E. Martenson; Vivian Liithy; Gladys E. Deibler
- Book ID
- 111171509
- Publisher
- John Wiley and Sons
- Year
- 1981
- Tongue
- English
- Weight
- 939 KB
- Volume
- 36
- Category
- Article
- ISSN
- 0022-3042
No coin nor oath required. For personal study only.
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Some acidic lipids including sulfatide and phosphatidylinositol were found to increase greatly the rate of cathepsin D cleavage of the myelin basic protein. Since a similar effect was seen when the substrate was changed to cytochrome C, but not when the enzyme was changed to pepsin, these acidic lip
The multiple myelin basic protein (MBP) isoforms expressed by myelinating cells are now known to have different expression patterns. The relative abundance of the isoforms containing exon II is greater early in myelinogenesis, whereas in compact myelin the isoforms lacking this exon are more abundan