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Cleavage of plasma high molecular weight kininogen in surgical ICU patients

✍ Scribed by T. S. Karlsrud; L. Buø; A. O. Aasen; H. T. Johansen

Publisher
Springer
Year
1996
Tongue
English
Weight
564 KB
Volume
22
Category
Article
ISSN
1432-1238

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High-molecular-weight kininogen, a nonenzymatic glycoprotein of the intrinsic blood coagulation system, is proteolytically cleaved by kallikrein as an early event in the activation of this system. The light chain of cleaved kininogen retains the ability to form specific noncovalent complexes with pr