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Cleavage of intracellular hepatitis C RNA in the virus core protein coding region by deoxyribozymes

✍ Scribed by J. Trepanier; J. E. Tanner; R. L. Momparler; O. N. L. Le; F. Alvarez; C. Alfieri


Book ID
108885843
Publisher
John Wiley and Sons
Year
2006
Tongue
English
Weight
531 KB
Volume
13
Category
Article
ISSN
1352-0504

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## Abstract Substitution of amino acid (aa) 70 and/or 91 in the core region of HCV genotype 1b (HCV‐1b) is an important predictor of hepatocarcinogenesis, but its impact on the development of hepatocellular carcinoma (HCC) following eradication of HCV RNA by antiviral therapy is not clear. 1,273 pa