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Cleaning up procedure for Captopril determination in urine samples by a nonintrusive method

✍ Scribed by P. Passamonti; F. Pucciarelli


Publisher
John Wiley and Sons
Year
1995
Tongue
English
Weight
312 KB
Volume
7
Category
Article
ISSN
1040-0397

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✦ Synopsis


This communication suggests how the SIN ratio in the electrochemical determination of Captopril in urine samples can be simply improved. The proposed method invollves unselective degradation of the proteins present in urine samples by refrigerating them down to -196Β°C. The separation is accomplished via ultracentrifugation at room temperature in such a way that very little manipulation of the sample occurs. This physical method is a useful tool for reducing background noise due to adsorbable products and for handling the sample as little as possible.


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