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Classification of Aurora kinase inhibitors by self-organizing map (SOM) and support vector machine (SVM)

✍ Scribed by Yan, Aixia; Nie, Xianglei; Wang, Kai; Wang, Maolin


Book ID
120268674
Publisher
Elsevier Science
Year
2013
Tongue
French
Weight
725 KB
Volume
61
Category
Article
ISSN
0223-5234

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Classification of Aurora-A Kinase Inhibi
✍ Liyu Wang; Zhi Wang; Aixia Yan; Qipeng Yuan πŸ“‚ Article πŸ“… 2011 πŸ› Wiley (John Wiley & Sons) 🌐 English βš– 469 KB

## Abstract Two classification models of 148 Aurora‐A kinase inhibitors were developed to separate active and weakly potent active inhibitors of Aurora‐A kinase. Each molecule was represented by 12 selected molecular descriptors calculated by the ADRIANA.Code. Then the classification models were bu