Lissencephaly is a rare developmental disorder resulting from impaired neural migration occurring from 6 to 15 weeks' gestation.' In its most severe form, it results in complete absence of gyri and sulci, and is called agyria. In other cases, there may be only a few abnormal gyri. Prenatal diagnosis
β¦ LIBER β¦
Classical (Type I) Lissencephaly and Miller-Dieker Syndrome
β Scribed by Christine A. Matarese; Deborah L. Renaud
- Book ID
- 116825488
- Publisher
- Elsevier Science
- Year
- 2009
- Tongue
- English
- Weight
- 126 KB
- Volume
- 40
- Category
- Article
- ISSN
- 0887-8994
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Twelve cases of lissencephaly are reported. A high resolution chromosome study was performed on each in order to detect small chromosomal anomalies, undetectable with routine techniques. Only one case was shown to have an unbalanced karyotype with a microdeletion of the short arm of chromosome 17 (d