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Class IIa histone deacetylases: regulating the regulators

✍ Scribed by Martin, M; Kettmann, R; Dequiedt, F

Book ID: 118676985
Publisher: Nature Publishing Group
Year: 2007
Tongue: English
Weight: 260 KB
Volume: 26
Category: Article
ISSN: 0950-9232
DOI: 10.1038/sj.onc.1210613

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## Abstract Histone deacetylases (HDACs) are enzymes that catalyze the removal of acetyl groups from lysine residues in both histone and non‐histone proteins. They play a key role in the regulation of gene transcription and many other biological processes involving chromatin. Significantly, recent