## Abstract Inflammation‐mediated bone loss is a major feature of various bone diseases including rheumatoid arthritis, osteoarthritis and advanced periodontitis. Enhanced osteoclast development or activity at the inflammation site results in bone resorption. IL‐23 is a heterodimeric cytokine belon
✦ LIBER ✦
Class A scavenger receptor promotes osteoclast differentiation via the enhanced expression of receptor activator of NF-κB (RANK)
✍ Scribed by Kenichi Takemura; Naomi Sakashita; Yukio Fujiwara; Yoshihiro Komohara; XiaoFeng Lei; Koji Ohnishi; Hiroshi Suzuki; Tatsuhiko Kodama; Hiroshi Mizuta; Motohiro Takeya
- Book ID
- 116299690
- Publisher
- Elsevier Science
- Year
- 2010
- Tongue
- English
- Weight
- 664 KB
- Volume
- 391
- Category
- Article
- ISSN
- 0006-291X
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## Abstract Receptor activator of NFκB ligand (RANKL), RANK, and osteoprotegerin (OPG) represent the key regulators of bone metabolism both in normal and pathological conditions, including bone metastases. To our knowledge, no previous studies investigated and compared RANK expression in primary tu