Clarity in the clinical medical literature

✍ Scribed by Murphy, William M.

• Publisher: John Wiley and Sons
• Year: 2000
• Tongue: English
• Weight: 59 KB
• Volume: 90
• Category: Article
• ISSN: 0008-543X
• DOI: 10.1002/(sici)1097-0142(20000425)90:2<71::aid-cncr1>3.0.co;2-2

✦ Synopsis

Cohen that reviews currently available and developing modalities for the early detection of recurrent urothelial neoplasms. 1 The authors list and briefly describe Ͼ 25 specific substances that appear to have sufficient sensitivity and specificity to be considered in the follow-up testing of patients. These substances include blood group antigens, total DNA, nuclear matrix proteins, cytokeratins, genes and gene products, abnormal chromosomes, fibrin degradation products, and growth factors. The literature regarding the subject already is so vast that even the 100 references cited for authority hardly begin to cover the field. The presentation is upbeat, seeming to promise imminent success in our ability to improve the health of patients presenting with "superficial" urothelial neoplasms. In fact, some form of the word "significant" appears frequently in the text, often preceding the words "promise" or "potential." The theme can be summarized as follows: