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Clarification of studies on the origin of thymic lymphocytes

✍ Scribed by Volpe, E. Peter ;Tompkins, Robert ;Reinschmidt, Dana

Publisher
John Wiley and Sons
Year
1979
Tongue
English
Weight
619 KB
Volume
208
Category
Article
ISSN
0022-104X

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✦ Synopsis

Abstract

The thesis that lymphocytes originate in situ by the direct transformation of epithelial cells within the thymic primordium in anurous frogs is untenable. On the contrary, in both the leopard frog and the African clawed toad, the lymphocytes that first appear in the embryonic thymus are derived from extrathymic lymphopoietc cells that invade the developing organ. The exact source of origin of the invading lymphopoietic cells remains problematic.

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