We demonstrate that neural crest cell-cell adhesion, cell-substrate adhesion, and ultimately cell motility, are highly dependent on the balanced action of tyrosine kinases and tyrosine phosphatases. Neural crest cell migration on fibronectin is diminished in the presence of the tyrosine phosphatase
โฆ LIBER โฆ
CK2 as a positive regulator of Wnt signalling and tumourigenesis
โ Scribed by David C. Seldin; Esther Landesman-Bollag; Marganit Farago; Nicolas Currier; David Lou; Isabel Dominguez
- Publisher
- Springer
- Year
- 2005
- Tongue
- English
- Weight
- 433 KB
- Volume
- 274
- Category
- Article
- ISSN
- 0300-8177
No coin nor oath required. For personal study only.
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## Abstract **Background:** Wnt signalling plays a critical role in many developmental processes and tumorigenesis. Wnt/ฮฒโcatenin signalling induces the stabilization of cytosolic ฮฒโcatenin, which interacts with TCF/LEFโ1 transcription factors, thereby inducing expression of Wntโtarget genes. Recen
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