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cJun NH2-terminal kinase 1 (JNK1): roles in metabolic regulation of insulin resistance

โœ Scribed by Guadalupe Sabio; Roger J. Davis


Book ID
113931587
Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
275 KB
Volume
35
Category
Article
ISSN
0968-0004

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c-Jun NH2-terminal kinase 1 in hepatocyt
โœ Francisco Javier Cubero; Oliver Drvarov; Christian Trautwein ๐Ÿ“‚ Article ๐Ÿ“… 2010 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 365 KB

Nonalcoholic steatosis (fatty liver) is a major cause of liver dysfunction that is associated with insulin resistance and metabolic syndrome. The cJun NH 2 -terminal kinase 1 (JNK1) signaling pathway is implicated in the pathogenesis of hepatic steatosis and drugs that target JNK1 may be useful for