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Citreospirosteroid, a new metabolite of a hybrid strain KO 0011 derived from Penicillium citreo-viride B. IFO 6200 and 4692

✍ Scribed by Seiji Kosemura; Sota Uotsu; Shosuke Yamamura

Publisher
Elsevier Science
Year
1997
Tongue
French
Weight
110 KB
Volume
38
Category
Article
ISSN
0040-4039

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✦ Synopsis

A sterol with a spiro ring system of B/C rings, citreospirosteroid, has been isolated from the mycelium of a hybrid strain KO 001l derived from Penicillium citreo-viride B. IFO 6200 and 4692. Its stereostructure has also been elucidated on the basis of its spectral data. It inhibited the growth of hypocotyls of lettuce seedlings, but promoted the growth of roots of its seedlings.

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Two new metabolites, citreo-y-pyrone and citreothiopyrane A, with interesting biological activity have been isolated from the mycelia of hybrid strains KO 0201 and 0211 derived from Penicillium citreo-viride B. IFO 6200 and 4692. Their structures have been elucidated based on their spectral data. In