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Citicoline is not protective in experimental models of Huntington's disease

✍ Scribed by Stéphane Mievis; Marc Levivier; Gilbert Vassart; Jacques Brotchi; Catherine Ledent; David Blum


Book ID
116781018
Publisher
Elsevier Science
Year
2007
Tongue
English
Weight
412 KB
Volume
28
Category
Article
ISSN
0197-4580

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We studied whether combinations of botanical extracts enriched in either D 9 -tetrahydrocannabinol (D 9 -THC) or cannabidiol (CBD), which are the main constituents of the cannabis-based medicine Sativex, provide neuroprotection in rat models of Huntington's disease (HD). We used rats intoxicated wit