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Citicoline increases glutathione redox ratio and reduces caspase-3 activation and cell death in staurosporine-treated SH-SY5Y human neuroblastoma cells

✍ Scribed by Marta Barrachina; Julio Secades; Rafael Lozano; Cristina Gómez-Santos; Santiago Ambrosio; Isidro Ferrer


Book ID
113998714
Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
223 KB
Volume
957
Category
Article
ISSN
0006-8993

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Dopamine induces autophagic cell death a
✍ Cristina Gómez-Santos; Isidre Ferrer; Antonio F. Santidrián; Marta Barrachina; J 📂 Article 📅 2003 🏛 John Wiley and Sons 🌐 English ⚖ 523 KB

## Abstract Free cytoplasmic dopamine may be involved in the genesis of neuronal degeneration in Parkinson's disease and other such diseases. We used SH‐SY5Y human neuroblastoma cells to study the effect of dopamine on cell death, activation of stress‐induced pathways, and expression of α‐synuclein