Cisplatin.An active drug in the treatment of disseminated gastric cancer
โ Scribed by Lawrence Leichman; Bruce McDonald; Aydin Dindogru; Michael Samson; Vainutis K. Vaitkevicius
- Publisher
- John Wiley and Sons
- Year
- 1984
- Tongue
- English
- Weight
- 735 KB
- Volume
- 53
- Category
- Article
- ISSN
- 0008-543X
No coin nor oath required. For personal study only.
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The synergistic antitumor activity of mitomycin C (MMC) and cisplatin (DDP) against the gastric cancer cell lines MKN-28 and MKN-45 was assessed in vitro using the MTT assay. The synergism of the two agents was evaluated in terms of the interaction index (1.1.). The sequence of MMC followed by DDP s
## Abstract During the past decades, despite considerable improvements in the management of gastric cancer, surgery reamains the main curative treatment. However, there is still debate about the extent of gastrectomy and lymphadenectomy, multivisceral resection, the requirement for reoperation for